Chemiluminescence-based detection of gastrointestinal malignancies.

摘要: Chemiluminescence is an established method for the in vitro serum monitoring of human tumors. may have additional utility vivo detection During carcinogenesis, tumors change their phenotype and proteins they express. Specifically, carcinogenesis esophagus stomach, enzymes that are normally only expressed small intestine brush border become ectopically precancerous cancerous lesions. Intestinal alkaline phosphatase lactase among expressed. We found specific chemiluminescent substrates be used situ intestinal unprocessed tissue. In this study, we demonstrate 1,2-dioxetane lesions from stomach. Copyright © 2009 John Wiley & Sons, Ltd.