Prospective controlled study of the safety and oncological outcomes of ELAPE procure with definitive anatomic landmarks versus conventional APE for lower rectal cancer
作者： Z. Shen , Y. Ye , X. Zhang , Q. Xie , M. Yin
DOI: 10.1016/J.EJSO.2015.01.017
关键词: Stage (cooking) 、 Neoadjuvant therapy 、 Prospective cohort study 、 Perforation (oil well) 、 Chemoradiotherapy 、 Survival rate 、 Abdominoperineal resection 、 Medicine 、 Colorectal cancer 、 Surgery
摘要: Abstract Background The use of extra-levator abdominoperineal resection (ELAPE) procedure for lower rectal cancer is controversial. It unclear whether the ELAPE could improve surgical safety and lead to better oncological outcomes. Methods Sixty-nine patients who underwent (36 cases) or conventional (APE; 33 between June 2011 February 2013 were prospectively investigated. Clinicopathological variables including blood loss, intraoperative perforation (IOP) rate, circumferential margin (CRM) involvement, lymph node harvest, postoperative complications, urinary sexual function, quality life (QOL), local recurrence rate survival recorded compared. Results Blood loss (P = 0.021), perineal wound complication (P = 0.039), IOP (P = 0.028), (P = 0.034) significantly less frequent in group. There was greater CRM involvement APE group but no statistical difference two groups. Urinary function QOL not different Overall progression-free groups, even when analyzed according TNM stage, T N with without neoadjuvant chemoradiotherapy. In there complications younger elderly (age ≥60). Conclusions definitive anatomic landmarks demonstrated decreased elderly, improvements compared procedure.
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