Early detection of gastric cancer beyond endoscopy - new methods.
作者： Aija Linē , Mārcis Leja
DOI: 10.1016/J.BPG.2021.101731
关键词: microRNA 、 Early detection 、 Endoscopy 、 Therapy monitoring 、 Extracellular vesicles 、 Cancer research 、 Cancer 、 Medicine
摘要: Early detection of gastric cancer is remaining a challenge. This review summarizes current knowledge on non-invasive methods that could be used for the purpose. The role of traditional cancer markers such as CEA, CA 72-4, CA 19-9, CA 15-3, and CA 12-5 lies mainly in therapy monitoring than early detection. Most extensive studied biomarkers (pepsinogens, ABC method) are aiming at the detection of precancerous lesions with modest sensitivity for cancer. Tests based on the detection of cancer-specific methylation …
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