Circulating Tumor Cell Clusters Are Oligoclonal Precursors of Breast Cancer Metastasis
作者： Nicola Aceto , Aditya Bardia , David T. Miyamoto , Maria C. Donaldson , Ben S. Wittner
DOI: 10.1016/J.CELL.2014.07.013
关键词: Metastasis 、 Plakoglobin 、 Primary tumor 、 Cancer research 、 Cell culture 、 Biology 、 Circulating tumor cell 、 Immunology 、 Single-cell analysis 、 Cancer 、 Breast cancer
摘要: Circulating tumor cell clusters (CTC clusters) are present in the blood of patients with cancer but their contribution to metastasis is not well defined. Using mouse models with tagged …
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Isaiah J. Fidler, The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited Nature Reviews Cancer. ,vol. 3, pp. 453- 458 ,(2003) , 10.1038/NRC1098
Eric R. Fearon, Karen M. Hajra, Kathleen R. Cho, Gang Hu, Gang Hu, Barbara Kolligs, Masachika Tani, Frank T. Kolligs, γ-Catenin is regulated by the APC tumor suppressor and its oncogenic activity is distinct from that of β-catenin Genes & Development. ,vol. 14, pp. 1319- 1331 ,(2000) , 10.1101/GAD.14.11.1319
J Kleinerman, L A Liotta, M G Saidel, The significance of hematogenous tumor cell clumps in the metastatic process Cancer Research. ,vol. 36, pp. 889- 894 ,(1976)
Ugo Cavallaro, Gerhard Christofori, Cell adhesion and signalling by cadherins and Ig-CAMs in cancer Nature Reviews Cancer. ,vol. 4, pp. 118- 132 ,(2004) , 10.1038/NRC1276
D. G. Duda, A. M. M. J. Duyverman, M. Kohno, M. Snuderl, E. J. A. Steller, D. Fukumura, R. K. Jain, Malignant cells facilitate lung metastasis by bringing their own soil Proceedings of the National Academy of Sciences of the United States of America. ,vol. 107, pp. 21677- 21682 ,(2010) , 10.1073/PNAS.1016234107
Yang Li, Lihua Zou, Qiyuan Li, Benjamin Haibe-Kains, Ruiyang Tian, Yan Li, Christine Desmedt, Christos Sotiriou, Zoltan Szallasi, J Dirk Iglehart, Andrea L Richardson, Zhigang Charles Wang, Amplification of LAPTM4B and YWHAZ contributes to chemotherapy resistance and recurrence of breast cancer Nature Medicine. ,vol. 16, pp. 214- 218 ,(2010) , 10.1038/NM.2090
Shahram Hakimelahi, Henry R. Parker, Anita J. Gilchrist, Michele Barry, Zhi Li, R. Chris Bleackley, Manijeh Pasdar, Plakoglobin Regulates the Expression of the Anti-apoptotic Protein BCL-2 Journal of Biological Chemistry. ,vol. 275, pp. 10905- 10911 ,(2000) , 10.1074/JBC.275.15.10905
Deborah Alford, Joyce Taylor-Papadimitriou, Cell adhesion molecules in the normal and cancerous mammary gland. Journal of Mammary Gland Biology and Neoplasia. ,vol. 1, pp. 207- 218 ,(1996) , 10.1007/BF02013644
Sendurai A. Mani, Wenjun Guo, Mai-Jing Liao, Elinor Ng. Eaton, Ayyakkannu Ayyanan, Alicia Y. Zhou, Mary Brooks, Ferenc Reinhard, Cheng Cheng Zhang, Michail Shipitsin, Lauren L. Campbell, Kornelia Polyak, Cathrin Brisken, Jing Yang, Robert A. Weinberg, The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells Cell. ,vol. 133, pp. 704- 715 ,(2008) , 10.1016/J.CELL.2008.03.027
A. J. Minn, G. P. Gupta, D. Padua, P. Bos, D. X. Nguyen, D. Nuyten, B. Kreike, Y. Zhang, Y. Wang, H. Ishwaran, J. A. Foekens, M. van de Vijver, J. Massague, Lung metastasis genes couple breast tumor size and metastatic spread Proceedings of the National Academy of Sciences of the United States of America. ,vol. 104, pp. 6740- 6745 ,(2007) , 10.1073/PNAS.0701138104