Structural basis of Keap1 interactions with Nrf2.
作者： Peter Canning , Fiona J. Sorrell , Alex N. Bullock
DOI: 10.1016/J.FREERADBIOMED.2015.05.034
关键词: Cullin 、 Ubiquitin 、 Biology 、 Ubiquitin ligase 、 KEAP1 、 Signal transduction 、 Gene 、 Transactivation 、 Neurodegeneration 、 Cell biology
摘要: … Keap1, allowing Nrf2 protein levels to accumulate for the transactivation of critical stress response genes. Consequently, the Keap1–… the structure determination of Keap1 and its protein …
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