Association of Cerebrovascular Events With Antidepressant Use: A Case-Crossover Study
作者： Chi-Shin Wu , Sheng-Chang Wang , Yu-Cheng Cheng , Susan Shur-Fen Gau
DOI: 10.1176/APPI.AJP.2010.10071064
关键词: Emergency medicine 、 Stroke 、 Antidepressant 、 Odds 、 Mood 、 Confounding 、 Odds ratio 、 Crossover study 、 Psychiatry 、 Confidence interval 、 Medicine 、 Psychiatry and Mental health
摘要: Objective:The authors sought to assess the risk of cerebrovascular events associated with use antidepressant medications. Method:The conducted a case-crossover study 24,214 patients stroke enrolled in National Health Insurance Research Database Taiwan from 1998 2007. The compared rates during case and control time windows 7, 14, 28 days. Adjustments were made for time-dependent variables, such as health system utilization proposed confounding Stratified analyses performed valuing interaction between age, sex, presence mood disorder, type, severity chronic illness, duration treatment. A conditional logistic regression model was used determine odds windows. Results:The adjusted ratio exposure 1.48 (95% confidence interval=1.37–1.59) using 14-day...
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