The reach of the genome signature in prokaryotes

作者: Mark WJ van Passel , Eiko E Kuramae , Angela CM Luyf , Aldert Bart , Teun Boekhout

DOI: 10.1186/1471-2148-6-84

关键词: BiologyGenomeGenome evolutionGeneticsGenome sizeSyntenyGenome projectReference genomeComputational biologyGene densityENCODE

摘要: Background With the increased availability of sequenced genomes there have been several initiatives to infer evolutionary relationships by whole genome characteristics. One these studies suggested good congruence between synteny, shared gene content, 16S ribosomal DNA identity, codon usage and signature in prokaryotes. Here we rigorously test phylogenetic signal signature, which consists genome-specific relative frequencies dinucleotides, on 334 prokaryotic sequences.

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