作者: Glenn McGall
DOI:
关键词: Nucleotide 、 High density 、 Combinatorial chemistry 、 Chemistry 、 Biochemistry 、 Oligonucleotide Arrays 、 Oligonucleotide 、 Nucleic acid
摘要: Methods are provided for fabricating high density oligonucleotide arrays with activators. According to the disclosed methods preparing on a solid support, following steps provided: a) providing support having surface comprising functional groups; b) attaching an activated nucleotide group in presence of activator; c) repeating step form array at least 100 different oligonucleotides/cm 2 .