Reducing product inhibition in nucleic acid-templated ligation reactions: DNA-templated cycligation.

作者: Alexander Roloff , Oliver Seitz

DOI: 10.1002/CBIC.201300516

关键词: BifunctionalLigationChemical ligationDNAChemistryProduct inhibitionStereochemistryPeptide nucleic acidNucleic acidNative chemical ligation

摘要: … a potentially generic approach to reduce product inhibition in nucleic acid-programmed ligation … We showed that the template first triggered a native chemical ligation reaction. Secondly, …

参考文章(84)
A. Luther, R. Brandsch, G. von Kiedrowski, Surface-promoted replication and exponential amplification of DNA analogues Nature. ,vol. 396, pp. 245- 248 ,(1998) , 10.1038/24343
Yanzheng Xu, Nilesh B. Karalkar, Eric T. Kool, Nonenzymatic autoligation in direct three-color detection of RNA and DNA point mutations Nature Biotechnology. ,vol. 19, pp. 148- 152 ,(2001) , 10.1038/84414
Amos Mattes, Oliver Seitz, Sequence fidelity of a template-directed PNA-ligation reaction. Chemical Communications. pp. 2050- 2051 ,(2001) , 10.1039/B106109G
Manuel Röthlingshöfer, Katarzyna Gorska, Nicolas Winssinger, Nucleic acid-templated energy transfer leading to a photorelease reaction and its application to a system displaying a nonlinear response. Journal of the American Chemical Society. ,vol. 133, pp. 18110- 18113 ,(2011) , 10.1021/JA2086504
A. W. SCHWARTZ, L. E. ORGEL, Template-Directed Synthesis of Novel, Nucleic Acid-Like Structures Science. ,vol. 228, pp. 585- 587 ,(1985) , 10.1126/SCIENCE.228.4699.585
Anne Erben, Tom N. Grossmann, Oliver Seitz, DNA-instructed acyl transfer reactions for the synthesis of bioactive peptides. Bioorganic & Medicinal Chemistry Letters. ,vol. 21, pp. 4993- 4997 ,(2011) , 10.1016/J.BMCL.2011.05.027
Simon Ficht, Amos Mattes, Oliver Seitz, Single-nucleotide-specific PNA-peptide ligation on synthetic and PCR DNA templates. Journal of the American Chemical Society. ,vol. 126, pp. 9970- 9981 ,(2004) , 10.1021/JA048845O
Mikkel F. Jacobsen, Emiliano Cló, Andriy Mokhir, Kurt V. Gothelf, Model systems for activation of nucleic acid encoded prodrugs. ChemMedChem. ,vol. 2, pp. 793- 799 ,(2007) , 10.1002/CMDC.200700013
Raphael M. Franzini, Eric T. Kool, Efficient nucleic acid detection by templated reductive quencher release. Journal of the American Chemical Society. ,vol. 131, pp. 16021- 16023 ,(2009) , 10.1021/JA904138V
Kazuhito Tanabe, Hiroyuki Nakata, Shin Mukai, Sei-ichi Nishimoto, Modulated drug release from the stem-and-loop structured oligodeoxynucleotide upon UV-A irradiation in the presence of target DNA. Organic and Biomolecular Chemistry. ,vol. 3, pp. 3893- 3897 ,(2005) , 10.1039/B510608G