Explanations for the heterogeneity of splenic enhancement derived from blood flow kinetic measurements using dynamic contrast-enhanced CT (DCE-CT)
作者： Alexander W Sauter , Daniel Spira , Maximilian Schulze , Marius S Horger
关键词: Cirrhosis 、 Nuclear medicine 、 Perfusion 、 Medicine 、 Blood volume 、 Infiltration (medical) 、 Perfusion scanning 、 Portal hypertension 、 Spleen 、 Blood flow 、 Radiology
摘要: BackgroundThe heterogeneity of splenic computed tomography (CT) attenuation is still not fully understood. A differentiation these enhancement patterns and other conditions such as diffuse spleen infiltration can be challenging.PurposeTo understand the underlying physiological mechanisms flow in normal cirrhosis patients by quantifying perfusion parameters blood (BF), volume (BV), time to peak (TTP), extraction product (Ktrans), mean transit (MTT) using dynamic contrast-enhanced CT (DCE-CT).Material MethodsSixteen without or hepatic disease 16 with liver were retrospectively analyzed. Perfusion assessment included rapidly slowly enhancing areas spleen, entire volume, well intra- inter-observer reliability analysis.ResultsSignificant differences between found controls for BF (109.8 mL/100 mL/min vs. 63.5 mL/100 mL/min), BV (37.1 mL/...
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