Leukocidin genes lukF-P83 and lukM are associated with taphylococcus aureus clonal complexes 151, 479 and 133 isolated from bovine udder infections in Thuringia, Germany

摘要: Staphylococcus aureus is one of the most important causal agents bovine mastitis. Population studies on isolates have identified considerable genetic heterogeneity among strains causing The aim this study was to investigate contribution different clonal complexes and occurrence virulence factors resistance determinants within isolates. A total 189 obtained from milk samples 34 dairy herds in German Federal State Thuringia were characterised by microarray technology. assigned eleven with CC151, CC479 CC133 being dominant (together 80.5%). methicillin gene mecA found four (2.1%), which belonged CC398. Enterotoxin genes could be detected 79.3% analysed 19 (10.1%) harboured a distinct allele toxic shock syndrome toxin gene, tst-RF122. striking finding present that almost all except isolate (151/152) belonging leukocidin lukF-P83 lukM, whereas no further other lineages possessed these genes. consistent lukF-P83/lukM dominating suggests an essential role etiology