Effects of resocialization on post-weaning social isolation-induced abnormal aggression and social deficits in rats.

摘要: As previously shown, rats isolated from weaning develop abnormal social and aggressive behavior characterized by biting attacks targeting vulnerable body parts of opponents, reduced attack signaling, increased defensive despite counts. Here we studied whether this form violent aggression could be reversed resocialization in adulthood. During the first weak resocialization, isolation-reared showed multiple deficits including defensiveness decreased huddling during sleep. Deficits were markedly attenuated second third weeks. Despite improved functioning groups, readily features a resident-intruder test performed after 3-week-long resocialization. Thus, post-weaning isolation-induced prosocial eliminated adulthood, but was resilient to treatment. Findings are compared those obtained humans who suffered early maltreatment, also show dysfunctional