Consequences of changing resistance patterns in urinary tract infections

摘要: Escherichia coli is responsible for the majority of uncomplicated urinary tract infections in healthy women. The rate resistance to cotrimoxazole (trimethoprim-sulfamethoxazole) among E. isolates from outpatients approaching and even exceeding 20% some regions USA. Evidence linking vitro with poorer clinical outcome cystitis pyelonephritis accumulating. Recent prior or current use antibacterials, recent hospitalisation comorbidity, e.g. diabetes mellitus, are associated a greater likelihood antibacterial resistance. In areas high cotrimoxazole, depending upon risks treatment failure, empirical therapy may have be altered. This article reviews literature on prevalence resistance, outcomes management community-acquired era increased uropathogen