Denaturation and aggregation of lysozyme in water-ethanol solution.
作者： Agnieszka Szymańska , Tomasz Hornowski , Genowefa Ślósarek
关键词: Solvation shell 、 Shear thinning 、 Denaturation (biochemistry) 、 Rheology 、 Newtonian fluid 、 Ethanol 、 Chromatography 、 Chemistry 、 Lysozyme 、 Chemical engineering 、 Viscosity
摘要: We have applied rheological methods for the analysis of ethanol-lysozyme interaction during process denaturation and aggregation protein. At low concentration ethanol a destruction hydration shell lysozyme is observed. With increase in structural transformation takes place. It leads to formation protein aggregate with an elongated structure. The characteristics lysozyme-water–ethanol solution changes from Newtonian pseudoplastic.
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