Adolescent transition among young people with perinatal HIV in high-income and low-income settings

摘要: Purpose of review To summarize evidence for health outcomes among adolescents and young people living with HIV (AYLHIV) who have transitioned to adult care/adulthood, views AYLHIV providers on the transition process, effect adolescent youth friendly services (AYFS) outcomes. Recent findings A total 43 studies were identified [n = 13 high-income countries (HICs), n 30 low-/middle-income (LMICs)]. In HICs, around 75% patients retained in care at approximately 4 years posttransition. LMICs, retention worsened from older adolescence into adulthood. Across both contexts, comparisons mortality, immunological, virological hampered by a limited number and/or different definitions study durations. reported several factors that could aid AYFS had generally positive Summary Overall, varied context; direct comparison was severely inclusion populations (sometimes small numbers lack groups), use outcome definitions, varying follow-up duration, specific process LMICs. Future need consider harmonizing implementing unique patient identifiers, data linkage techniques improve base long-term