Tracing ancestry with methylation patterns: most crypts appear distantly related in normal adult human colon
作者： Kyoung-Mee Kim , Darryl Shibata
关键词: Human colon 、 Methylation 、 DNA methylation 、 Medicine 、 Common descent 、 Evolutionary biology
摘要: Background The ability to discern ancestral relationships between individual human colon crypts is limited. Widely separated likely trace their common ancestors a time around birth, but closely spaced adult may share more recent if they frequently divide by fission form clonal patches. Alternatively, be long-lived structures that infrequently or die.
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N A Wright, H S Park, R A Goodlad, Crypt fission in the small intestine and colon. A mechanism for the emergence of G6PD locus-mutated crypts after treatment with mutagens. American Journal of Pathology. ,vol. 147, pp. 1416- 1427 ,(1995)
Allan Spradling, Daniela Drummond-Barbosa, Toshie Kai, Stem cells find their niche Nature. ,vol. 414, pp. 98- 104 ,(2001) , 10.1038/35102160
Nicholas A. Wright, Epithelial stem cell repertoire in the gut: clues to the origin of cell lineages, proliferative units and cancer International Journal of Experimental Pathology. ,vol. 81, pp. 117- 143 ,(2002) , 10.1046/J.1365-2613.2000.00146.X
R Holliday, J. Pugh, How Are Alkynes Scrambled Science. ,vol. 308, pp. 216- 217 ,(2005) , 10.1126/SCIENCE.1111098
Shin-Ichi Nakamura, Junko Goto, Masahiko Kitayama, Isamu Kino, Application of the crypt-isolation technique to flow-cytometric analysis of DNA content in colorectal neoplasms Gastroenterology. ,vol. 106, pp. 100- 107 ,(1994) , 10.1016/S0016-5085(94)94651-5
J.-P. Issa, CpG-island methylation in aging and cancer. Current Topics in Microbiology and Immunology. ,vol. 249, pp. 101- 118 ,(2000) , 10.1007/978-3-642-59696-4_7
Y. Yatabe, S. Tavare, D. Shibata, Investigating stem cells in human colon by using methylation patterns Proceedings of the National Academy of Sciences of the United States of America. ,vol. 98, pp. 10839- 10844 ,(2001) , 10.1073/PNAS.191225998
A. P. Maskens, Rose-Marie Dujardin-Loits, KINETICS OF TISSUE PROLIFERATION IN COLORECTAL MUCOSA DURING POST‐NATAL GROWTH Cell Proliferation. ,vol. 14, pp. 467- 477 ,(1981) , 10.1111/J.1365-2184.1981.TB00553.X
Hazel Cheng, Matthew Bjerknes, Jack Amar, Geoffrey Gardiner, Crypt production in normal and diseased human colonic epithelium Anatomical Record-advances in Integrative Anatomy and Evolutionary Biology. ,vol. 216, pp. 44- 48 ,(1986) , 10.1002/AR.1092160108
J. Totafurno, M. Bjerknes, H. Cheng, The crypt cycle. Crypt and villus production in the adult intestinal epithelium Biophysical Journal. ,vol. 52, pp. 279- 294 ,(1987) , 10.1016/S0006-3495(87)83215-0