[N,P]-pyrrole PdCl2 complexes catalyzed the formation of dibenzo-α-pyrone and lactam analogues
作者： J. V. Suárez-Meneses , A. Oukhrib , M. Gouygou , M. Urrutigoïty , J.-C. Daran
DOI: 10.1039/C6DT01022A
关键词: Medicinal chemistry 、 Lactam 、 Pyrone 、 Catalysis 、 Stereochemistry 、 Ring (chemistry) 、 Intramolecular force 、 Chemistry 、 Phosphole 、 Pyrrole 、 Palladium
摘要: We herein report the synthesis and catalytic application of a new family [N,P] ligands based on pyrrole ring with alpha-phosphine or phosphole units. Their palladium complexes (3a-d) were obtained in very good yields their properties evaluated direct intramolecular arylation to obtain both benzopyranones phenanthridinones. The air stable complex 3a exhibited best performance this series complexes, using 1 mol% catalyst combination microwaves promote reaction.
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