Angiosarcoma associated with germ cell tumors

作者: Thomas M. Ulbright , Steven A. Clark , Lawrence H. Einhorn

DOI: 10.1016/S0046-8177(85)80013-7

关键词: ComplicationNeoplasmRadiation therapyTeratomaGerm cell tumorsAngiosarcomaPathologyGerm cellChemotherapyBiologyPathology and Forensic Medicine

摘要: In two patients with malignant germ cell tumors angiosarcoma developed through apparently different mechanisms. one case the probably as a complication of therapeutic radiation, since radiation changes were demonstrated in tissue adjacent to neoplasm and was not associated elements tumor. The absence does support development from teratoma. second case, however, it is likely that result change within teratomatous foci, angiosarcomatous intermingled patient's primary tumor contained atypical well prominent vascular proliferation. Malignant components phenomenon increasing importance this era effective chemotherapy for tumors. potential testicular carcinoma has been reported previously.

参考文章(22)
Robert M. Donnell, Paul Peter Rosen, Philip H. Lieberman, Richard J. Kaufman, Saul Kay, David W. Braun, David W. Kinne, Angiosarcoma and other vascular tumors of the breast. The American Journal of Surgical Pathology. ,vol. 5, pp. 629- 642 ,(1981) , 10.1097/00000478-198110000-00005
Walter H. C. Burgdorf, Kiyoshi Mukai, Juan Rosai, Immunohistochemical identification of factor VIII-related antigen in endothelial cells of cutaneous lesions of alleged vascular nature. American Journal of Clinical Pathology. ,vol. 75, pp. 167- 171 ,(1981) , 10.1093/AJCP/75.2.167
PAUL D. BERK, Vinyl Chloride-Associated Liver Disease Annals of Internal Medicine. ,vol. 84, pp. 717- 731 ,(1976) , 10.7326/0003-4819-84-6-717
RICHARD J. REED, Lymphangiosarcomas of the Scalp Archives of Dermatology. ,vol. 94, pp. 396- 402 ,(1966) , 10.1001/ARCHDERM.1966.01600280014002
Markku Miettinen, Veli-Pekka Lehto, Ismo Virtanen, Postmastectomy angiosarcoma (Stewart-Treves syndrome). Light-microscopic, immunohistological, and ultrastructural characteristics of two cases. The American Journal of Surgical Pathology. ,vol. 7, pp. 329- 339 ,(1983) , 10.1097/00000478-198306000-00004
Stephen D Williams, Lawrence H Einhorn, F Anthony Greco, Robert Oldham, Ronald Fletcher, None, VP-16–213 salvage therapy for refractory germinal neoplasms Cancer. ,vol. 46, pp. 2154- 2158 ,(1980) , 10.1002/1097-0142(19801115)46:10<2154::AID-CNCR2820461008>3.0.CO;2-3
Karl T. K. Chen, Klaus D. Hoffman, Ed J. Hendricks, Angiosarcoma following therapeutic irradiation. Cancer. ,vol. 44, pp. 2044- 2048 ,(1979) , 10.1002/1097-0142(197912)44:6<2044::AID-CNCR2820440614>3.0.CO;2-U