The relationship of sperm parameters to cycle fecundity in superovulated women undergoing intrauterine insemination.
作者： Peter M. Horvath , Michael Bohrer , Robert M. Shelden , Ekkehard Kemmann
DOI: 10.1016/S0015-0282(16)60857-9
关键词: Insemination 、 Pregnancy 、 Andrology 、 Fecundity 、 Menotropin 、 Semen 、 Biology 、 Sperm 、 Artificial insemination 、 Pregnancy rate
摘要: Semen parameters of raw and prepared (post-swim-up) specimens from 451 cycles ofintrauterine insemination (IUI) were analyzed in relation to cycle fecundity 232 patientsundergoing ovarian stimulation with sequential clomiphene citrate/menotropin therapy. Pregnancy occurred 42 cycles, resulting an overall pregnancy rate 17. 7%, a 9.3%. Cycle was positively correlated the post-swim-up log sperm density ( r = 0.994), total motile inseminated( 0.964; inseminates limited maximum 20 million sperm). Post-swim-up motility did not correlate 0.308) fecundity; however, most had > 40% post-swim-up. Only one when less than 1 inseminated (38 cycles) , which resulted 2.6% for these cycles. This may represent threshold effectiveness IUI this setting. Highest obtained inseminate containing approximately 10 or more sperm. Parameters samples well specimens. Analysis semen can provide useful prognostic information women undergoing stimulation; is helpful counseling patients regarding their chances success
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sci-hub.se 参考文章(17)
Daniel W. Cramer, Alexander M. Walker, Isaac Schiff, Statistical methods in evaluating the outcome of infertility therapy Fertility and Sterility. ,vol. 32, pp. 80- 86 ,(1979) , 10.1016/S0015-0282(16)44120-8
Peter M. Horvath, Martha Beck, Michael K. Bohrer, Robert M. Shelden, Ekkehard Kemmann, A prospective study on the lack of development of antisperm antibodies in women undergoing intrauterine insemination American Journal of Obstetrics and Gynecology. ,vol. 160, pp. 631- 637 ,(1989) , 10.1016/S0002-9378(89)80045-6
John Kerin, Patrick Quinn, Washed Intrauterine Insemination in the Treatment of Oligospermic Infertility Seminars in Reproductive Medicine. ,vol. 5, pp. 23- 33 ,(1987) , 10.1055/S-2007-1021850
Constance Mao, David A. Grimes, The sperm penetration assay: Can it discriminate between s fertile and infertile men? American Journal of Obstetrics and Gynecology. ,vol. 159, pp. 279- 286 ,(1988) , 10.1016/S0002-9378(88)80068-1
William C. Dodson, Claude L. Hughes, A.F. Haney, Multiple pregnancies conceived with intrauterine insemination during superovulation: An evaluation of clinical characteristics and monitored parameters of conception cycles American Journal of Obstetrics and Gynecology. ,vol. 159, pp. 382- 385 ,(1988) , 10.1016/S0002-9378(88)80089-9
Abraham Ge, Maroulis Gb, Marshall, Evaluation of ovulation and corpus luteum function using measurements of plasma progesterone. Obstetrics & Gynecology. ,vol. 44, pp. 522- ,(1974)
Stephen J. Harris, Michael P. Milligan, Gordon M. Masson, K. John Dennis, Improved separation of motile sperm in asthenospermia and its application to artificial insemination homologous (AIH) Fertility and Sterility. ,vol. 36, pp. 219- 221 ,(1981) , 10.1016/S0015-0282(16)45682-7
LJ Burkman, CC Coddington, DR Franken, The hemizona assay (HZA): development of a diagnostic test for the binding of human spermatozoa to the human hemizona pellucida to predict fertilization potential * † ‡ Fertility and Sterility. ,vol. 49, pp. 688- 697 ,(1989) , 10.1016/0020-7292(89)90506-7
Edward E. Wallach, Nancy C. Allen, Carl M. Herbert, Wayne S. Maxson, B. Jane Rogers, Michael P. Diamond, Anne Colston Wentz, Intrauterine insemination: a critical review. Fertility and Sterility. ,vol. 44, pp. 569- 580 ,(1985) , 10.1016/S0015-0282(16)48969-7
Trish Berger, Richard P. Marrs, Dean L. Moyer, Comparison of techniques for selection of motile spermatozoa Fertility and Sterility. ,vol. 43, pp. 268- 273 ,(1985) , 10.1016/S0015-0282(16)48384-6