A prospective study on the lack of development of antisperm antibodies in women undergoing intrauterine insemination
作者： Peter M. Horvath , Martha Beck , Michael K. Bohrer , Robert M. Shelden , Ekkehard Kemmann
DOI: 10.1016/S0002-9378(89)80045-6
关键词:
摘要: To test the hypothesis that intrauterine insemination with washed spermatozoa induces antisperm antibody formation, we measured serum levels by Immunobead technique in a population of women receiving exogenous gonadotropins. Antibody were before therapy (baseline) and then serially during subsequent stimulation cycles, for maximum six cycles. Twenty-eight patients underwent insemination; each patient served as her own control. An additional 25 treated gonadotropins but did not undergo they external controls. Antisperm who concomitant compared those not. Of 53 enrolled patients, 18 completed treatment 35 achieved pregnancy Forty-five (85%) had 25% (28% 42%, respectively). Mean binding was similar (
sci-hub.se 参考文章(16)
Edward E. Wallach, Richard Bronson, George Cooper, David Rosenfeld, Sperm antibodies: their role in infertility* Fertility and Sterility. ,vol. 42, pp. 171- 183 ,(1984) , 10.1016/S0015-0282(16)48009-X
Sidney Kibrick, David L. Belding, Beulah Merrill, Methods for the Detection of Antibodies against Mammalian Spermatozoa Fertility and Sterility. ,vol. 3, pp. 430- 438 ,(1952) , 10.1016/S0015-0282(16)31026-3
Shinzo Isojima, Tien Shun Li, Yoshio Ashitaka, Immunologic analysis of sperm-immobilizing factor found in sera of women with unexplained sterility American Journal of Obstetrics and Gynecology. ,vol. 101, pp. 677- 683 ,(1968) , 10.1016/0002-9378(68)90307-4
Gabor Huszar, Alan DeCherney, The Role of Intrauterine Insemination in the Treatment of Infertile Couples: The Yale Experience Seminars in Reproductive Medicine. ,vol. 5, pp. 11- 21 ,(1987) , 10.1055/S-2007-1021849
D. Mortimer, A. A. Templeton, Sperm transport in the human female reproductive tract in relation to semen analysis characteristics and time of ovulation Reproduction. ,vol. 64, pp. 401- 408 ,(1982) , 10.1530/JRF.0.0640401
Kremer J, A new technique for intrauterine insemination. International Journal of Fertility. ,vol. 24, pp. 53- ,(1979)
Edward E. Wallach, Nancy C. Allen, Carl M. Herbert, Wayne S. Maxson, B. Jane Rogers, Michael P. Diamond, Anne Colston Wentz, Intrauterine insemination: a critical review. Fertility and Sterility. ,vol. 44, pp. 569- 580 ,(1985) , 10.1016/S0015-0282(16)48969-7
Ekkehard Kemmann, James R. Jones, Sequential clomiphene citrate-menotropin therapy for induction or enhancement of ovulation Fertility and Sterility. ,vol. 39, pp. 772- 779 ,(1983) , 10.1016/S0015-0282(16)47116-5
Sandra Ann Carson, Jill Reiher, Antonio Scommegna, Gail S. Prins, Antibody binding patterns in infertile males and females as detected by immunobead test, gel-agglutination test, and sperm immobilization test. Fertility and Sterility. ,vol. 49, pp. 487- 492 ,(1988) , 10.1016/S0015-0282(16)59778-7
Diane G. Hammitt, Michelle M. Muench, Roger A. Williamson, Antibody binding to greater than 50% of sperm at the tail tip does not impair male fertility Fertility and Sterility. ,vol. 49, pp. 174- 177 ,(1988) , 10.1016/S0015-0282(16)59674-5