Peut-on optimiser l'insémination avec donneur ?

作者: R Wainer , F Fagnani

DOI: 10.1016/S1297-9589(00)00068-0

关键词: GynecologyAnalyse cout efficaciteIntra uterine inseminationDonor inseminationMedicine

摘要: Resume Objectif – Faire une evaluation comparative des techniques d’insemination avec donneur (IAD). Materiel et methode – Analyse etudes publiees sur l’IAD qui evaluent l’efficacite inseminations intra cervicales (IICD) uterines (IIUD), l’interet d’une stimulation de l’ovulation, les complications eventuelles le rapport cout–efficacite. Resultats – La meta-analyse la Cochrane database (dix essais comparatifs IIUD contre IICD, 2568 cycles d’IAD) retrouve un taux grossesse par cycle (TGC) 17,77 % en 7,68 % IICD. L’odd-ratio est 2,63 (IC 1,85 a 3,73). Compte tenu ces TGC, cout direct evolutive obtenue l’ordre 54 780 F pour l’IICD 25 675 l’IIUD. Conclusion – Si peut etre proposee patientes ayant excellente regularite ovulatoire, l’IIUD l’ovulation gonadotrophines aujourd’hui technique reference, ce d’autant plus que reglementation limite nombre d’IAD couple. En effet deux trois fois efficace l’IICD, elle consomme moitie moins paillettes, permet d’utiliser sperme qualite moyenne, n’entraine aucune complication particuliere condition savoir annuler s’il existe follicules preovulatoires, enfin son cout–efficacite largement favorable celui l’IICD.

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