Histiocytic disorders of the gastrointestinal tract

作者: Sönke Detlefsen , Christina R. Fagerberg , Lilian B. Ousager , Jan Lindebjerg , Niels Marcussen

DOI: 10.1016/J.HUMPATH.2012.05.010

关键词: Langerhans cell histiocytosisMalacoplakiaJuvenile xanthogranulomaGastrointestinal tractXanthogranulomatous inflammationWhipple DiseaseHistiocytosisDifferential diagnosisPathologyBiology

摘要: The morphologic diagnosis of histiocytic lesions the gastrointestinal tract can be challenging, and several disorders have to considered in their differential diagnosis. We present one most widespread examples xanthomatosis published so far give a short review on general. primary uncertain origin, Rosai-Dorfman disease, Langerhans cell histiocytosis, Erdheim-Chester are addressed. Reactive infectious conditions such as xanthomatosis, xanthogranulomatous inflammation, juvenile xanthogranuloma, Whipple's disease malacoplakia discussed well. also briefly go into neoplastic systemic diseases with secondary involvement like lysosomal storage disorders, pigmented lesions. Using panel histochemical stains immunohistochemical markers, together conventional microscopy, clinical information, imaging studies, established instances.

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