Review of Current Applications of Immunohistochemistry in Pediatric Nonneoplastic Gastrointestinal, Hepatobiliary, and Pancreatic Lesions

摘要: Immunohistochemical (IHC) stains are widely used by pathologists for a variety of considerations in the diagnostic workup pediatric nonneoplastic lesions gastrointestinal (GI), hepatic, biliary, and pancreatic lesions. The pathologic changes cover wide range types presentations, including inflammatory (bacterial viral), metaplastic, posttransplant lymphoproliferative, autoimmune, metabolic, degenerative, developmental, genetic conditions, among others. everyday practical value IHC covers primary identification, confirmation, differential, and/or exclusionary roles hands eyes minds practitioners. This article is intended to review discuss currently available GI, hepatobiliary, as encountered day-to-day practice clinicians. It reflects most recent methods with stated aim helping provide quick reference thereby facilitate broad GI related conditions population. tables handy on commonly covering that amenable light microscopic interpretation.