The polycomb group protein Bmi-1 represses the tumor suppressor PTEN and induces epithelial-mesenchymal transition in human nasopharyngeal epithelial cells
作者： Li-Bing Song , Jun Li , Wen-Ting Liao , Yan Feng , Chun-Ping Yu
DOI: 10.1172/JCI39374
关键词: Nasopharyngeal carcinoma 、 Cancer research 、 Epithelial–mesenchymal transition 、 Biology 、 PI3K/AKT/mTOR pathway 、 Gene silencing 、 PTEN 、 Nasopharyngeal neoplasm 、 Protein kinase B 、 Downregulation and upregulation
摘要: The polycomb group protein B lymphoma Mo-MLV insertion region 1 homolog (Bmi-1) is dysregulated in various cancers, and its upregulation strongly correlates with an invasive …
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