Estimation of size and number density of microbubbles based on analysis of frequency-dependent attenuation

摘要: A method of estimating the size and number density microbubbles in suspension is proposed, which matches theoretically calculated frequency dependent attenuation coefficient with experimental data. Assuming that distribution bubbles given by a log-normal function, three parameters (expected value standard deviation radius bubbles) Sonazoid® steady flow were estimated. Bubbles are exposed to ultrasound center 5 MHz mechanical indices 0.4, 0.5, 0.7, 1.1. The expected for estimated be 70–85 45–60% reference values case lower index, respectively. was 20–30 times smaller than values. This fundamental examination indicates can qualitatively evaluated proposed method.