Real-time physiological sensor-based liver-on-chip device for monitoring drug toxicity
作者： Hafiz Muhammad Umer Farooqi , Muhammad Asad Ullah Khalid , Kyung Hwan Kim , Sun Ryung Lee , Kyung Hyun Choi
关键词: Chemistry 、 Hepg2 cells 、 Drug toxicity 、 Biomedical engineering
摘要:
harvard.edu
sci-hub.st 参考文章(71)
Jyoti Srivastava, Diane L. Barber, Matthew P. Jacobson, Intracellular pH Sensors: Design Principles and Functional Significance Physiology. ,vol. 22, pp. 30- 39 ,(2007) , 10.1152/PHYSIOL.00035.2006
Nicholas J. Douville, Yi-Chung Tung, Ran Li, Jack D. Wang, Mohamed E.H. El-Sayed, Shuichi Takayama, Fabrication of two-layered channel system with embedded electrodes to measure resistance across epithelial and endothelial barriers. Analytical Chemistry. ,vol. 82, pp. 2505- 2511 ,(2010) , 10.1021/AC9029345
Ilka Wagner, Eva-Maria Materne, Sven Brincker, Ute Süßbier, Caroline Frädrich, Mathias Busek, Frank Sonntag, Dmitry A. Sakharov, Evgeny V. Trushkin, Alexander G. Tonevitsky, Roland Lauster, Uwe Marx, A dynamic multi-organ-chip for long-term cultivation and substance testing proven by 3D human liver and skin tissue co-culture Lab on a Chip. ,vol. 13, pp. 3538- 3547 ,(2013) , 10.1039/C3LC50234A
David Erickson, Dongqing Li, Integrated microfluidic devices Analytica Chimica Acta. ,vol. 507, pp. 11- 26 ,(2004) , 10.1016/J.ACA.2003.09.019
Aman U. Buzdar, Nuhad K. Ibrahim, Deborah Francis, Daniel J. Booser, Eva S. Thomas, Richard L. Theriault, Lajos Pusztai, Marjorie C. Green, Banu K. Arun, Sharon H. Giordano, Massimo Cristofanilli, Debra K. Frye, Terry L. Smith, Kelly K. Hunt, Sonja E. Singletary, Aysegul A. Sahin, Michael S. Ewer, Thomas A. Buchholz, Donald Berry, Gabriel N. Hortobagyi, Significantly Higher Pathologic Complete Remission Rate After Neoadjuvant Therapy With Trastuzumab, Paclitaxel, and Epirubicin Chemotherapy: Results of a Randomized Trial in Human Epidermal Growth Factor Receptor 2–Positive Operable Breast Cancer Journal of Clinical Oncology. ,vol. 23, pp. 3676- 3685 ,(2005) , 10.1200/JCO.2005.07.032
Kunyoo Shin, Vanessa C. Fogg, Ben Margolis, Tight Junctions and Cell Polarity Annual Review of Cell and Developmental Biology. ,vol. 22, pp. 207- 235 ,(2006) , 10.1146/ANNUREV.CELLBIO.22.010305.104219
Elke Thedinga, Axel Kob, Heiko Holst, Andreas Keuer, Sabine Drechsler, Ricarda Niendorf, Werner Baumann, Ingo Freund, Mirko Lehmann, Ralf Ehret, Online monitoring of cell metabolism for studying pharmacodynamic effects. Toxicology and Applied Pharmacology. ,vol. 220, pp. 33- 44 ,(2007) , 10.1016/J.TAAP.2006.12.027
R. Booth, S. Noh, H. Kim, A multiple-channel, multiple-assay platform for characterization of full-range shear stress effects on vascular endothelial cells. Lab on a Chip. ,vol. 14, pp. 1880- 1890 ,(2014) , 10.1039/C3LC51304A
Delphine Théard, Marcel A. Raspe, Dharamdajal Kalicharan, Dick Hoekstra, Sven C.D. van IJzendoorn, Formation of E-cadherin/beta-catenin-based adherens junctions in hepatocytes requires serine-10 in p27(Kip1). Molecular Biology of the Cell. ,vol. 19, pp. 1605- 1613 ,(2008) , 10.1091/MBC.E07-07-0661
Nicholas Ferrell, Ravi R. Desai, Aaron J. Fleischman, Shuvo Roy, H. David Humes, William H. Fissell, A microfluidic bioreactor with integrated transepithelial electrical resistance (TEER) measurement electrodes for evaluation of renal epithelial cells. Biotechnology and Bioengineering. ,vol. 107, pp. 707- 716 ,(2010) , 10.1002/BIT.22835