Targeting CD44, ABCG2 and CD133 markers using aptamers: in silico analysis of CD133 extracellular domain 2 and its aptamer

作者: Nithya Subramanian , Balachandran Akilandeswari , Anjali Bhutra , Mohamed Alameen , Umashankar Vetrivel

DOI: 10.1039/C5RA27072C

关键词: CD44Cancer stem cellExtracellularMolecular biologyPopulationAptamerChemistryCell cultureIn silicoCancer cell

摘要: … Our results confirms that the CD133 and CD44 aptamers have potential use for CSC targeting as they disintegrated the 3D cell culture model and lead to cell death. It will be of greater …

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