In Vitro Selection of Modified RNA Aptamers Against CD44 Cancer Stem Cell Marker

作者: Nidaa Ababneh , Walhan Alshaer , Omar Al-Louzi , Azmi Mahafzah , Mohammed El-Khateeb

DOI: 10.1089/NAT.2013.0423

关键词:

摘要: … isolated RNA aptamers bind specifically to CD44 molecules on the representative cell lines expressing this marker. With further characterization, the developed CD44 aptamers might …

参考文章(25)
J. Lynne Williams, Cancer Stem Cells ,(2009)
Mahendra P. Deonarain, Christina A. Kousparou, Agamemnon A. Epenetos, Antibodies targeting cancer stem cells: a new paradigm in immunotherapy? mAbs. ,vol. 1, pp. 12- 25 ,(2009) , 10.4161/MABS.1.1.7347
Steven J. Wang, Lilly Y.W. Bourguignon, Role of Hyaluronan-Mediated CD44 Signaling in Head and Neck Squamous Cell Carcinoma Progression and Chemoresistance American Journal of Pathology. ,vol. 178, pp. 956- 963 ,(2011) , 10.1016/J.AJPATH.2010.11.077
Michael Baumann, Mechthild Krause, CD44 - a cancer stem cell related biomarker with predictive potential for radiotherapy Clinical Cancer Research. ,vol. 16, pp. 5091- 5093 ,(2010) , 10.1158/1078-0432.CCR-10-2244
Kejing Zhang, Kwame Sefah, Lili Tang, Zilong Zhao, Guizhi Zhu, Mao Ye, Weijia Sun, Steve Goodison, Weihong Tan, A Novel Aptamer Developed for Breast Cancer Cell Internalization ChemMedChem. ,vol. 7, pp. 79- 84 ,(2012) , 10.1002/CMDC.201100457
Dalia López‐Colón, Elizabeth Jiménez, Mingxu You, Basri Gulbakan, Weihong Tan, Aptamers: turning the spotlight on cells Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology. ,vol. 3, pp. 328- 340 ,(2011) , 10.1002/WNAN.133
Jane E. Visvader, Geoffrey J. Lindeman, Cancer stem cells in solid tumours: accumulating evidence and unresolved questions Nature Reviews Cancer. ,vol. 8, pp. 755- 768 ,(2008) , 10.1038/NRC2499
Anoma Somasunderam, Varatharasa Thiviyanathan, Takemi Tanaka, Xin Li, Muniasamy Neerathilingam, Ganesh Lakshmana Rao Lokesh, Aman Mann, Yang Peng, Mauro Ferrari, Jim Klostergaard, David G. Gorenstein, Combinatorial selection of DNA thioaptamers targeted to the HA binding domain of human CD44 Biochemistry. ,vol. 49, pp. 9106- 9112 ,(2010) , 10.1021/BI1009503
Sarah Shigdar, Jia Lin, Yan Yu, Mile Pastuovic, Ming Wei, Wei Duan, RNA aptamer against a cancer stem cell marker epithelial cell adhesion molecule Cancer Science. ,vol. 102, pp. 991- 998 ,(2011) , 10.1111/J.1349-7006.2011.01897.X
Erik W. Orava, Nenad Cicmil, Jean Gariépy, Delivering cargoes into cancer cells using DNA aptamers targeting internalized surface portals Biochimica et Biophysica Acta. ,vol. 1798, pp. 2190- 2200 ,(2010) , 10.1016/J.BBAMEM.2010.02.004