Cancer stem cells in solid tumours: accumulating evidence and unresolved questions

作者: Jane E. Visvader , Geoffrey J. Lindeman

DOI: 10.1038/NRC2499

关键词: Cancer stem cellSelf renewalCellular mechanismProgenitor cellPathologyCancer researchBreast cancerCancer burdenCarcinogenesisPerivascular nicheBiologyOncology

摘要: Solid tumours are an enormous cancer burden and a major therapeutic challenge. The cancer stem cell (CSC) hypothesis provides an attractive cellular mechanism to account for …

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