The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin
作者： Bernd Greiner , Michel Eichelbaum , Peter Fritz , Hans-Peter Kreichgauer , Oliver von Richter
DOI: 10.1172/JCI6663
关键词: Digoxin 、 Talinolol 、 Pharmacology 、 Oral administration 、 Duodenum 、 Antibiotics 、 Concomitant 、 Volunteer 、 Pharmacokinetics 、 Medicine
摘要: Recent data point to the contribution of P-glycoprotein (P-gp) to digoxin elimination. On the basis of clinical observations of patients in whom digoxin levels decreased considerably …
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