Exploring the evolution of wolbachia compatibility types : A simulation approach

摘要: Wolbachia-induced cytoplasmic incompatibility (CI) is observed when males bearing the bacterium mate with uninfected females or a different Wolbachia variant; in such crosses, paternal chromosomes are lost at first embryonic mitosis, most often resulting developmental arrest. The molecular basis of CI currently unknown, but it useful to distinguish conceptually male and female sides this phenomenon: males, must do something, before shed from maturing sperm, that will disrupt functionality [this usually termed “the modification (mod) function”]; females, somehow restore viability, through what called rescue (resc) function.” occurrence crosses between variants demonstrates mod resc functions interact specific manner: pairs make compatibility types. We interested evolutionary process allowing diversification In an earlier model, based on main assumption can mutate independently, we have shown types evolve two-step process, involving drift variations second selection variations. This previous study has highlighted need for simulation-based models would include effects nondeterministic forces. simulation program fulfilling condition, us follow evolution under mutation, drift, selection. Most importantly, simulations suggest frame our likely be gradual new remaining partially compatible ancestral ones.