Hyperprolactinemia in polycystic ovary syndrome
作者： Anthony A. Luciano , Frederick K. Chapler , Barry M. Sherman
DOI: 10.1016/S0015-0282(16)47838-6
关键词: Hormone 、 Polycystic ovary 、 Internal medicine 、 Endocrinology 、 Hypothalamus 、 Luteinizing hormone 、 Testosterone 、 Medicine 、 Prolactin 、 Adrenocorticotropic hormone 、 Blood sampling
摘要: With the use of multiple blood sampling, prevalence hyperprolactinemia in 150 consecutive patients with polycystic ovary syndrome (PCO) was found to be 17%. To further compare these two groups PCO patients, pituitary responses gonadotropin-releasing hormone and thyrotropin-releasing adrenal dexamethasone suppression adrenocorticotropic stimulation were evaluated 40 normoprolactinemic 10 hyperprolactinemic patients. Adrenal pertubation tests normal both Besides higher levels prolactin, also had thyrotropin testosterone, a luteinizing hormone/follicle-stimulating ratio, lower follicle-stimulating hormone, hormone. Our data are consistent hypothesis that some cases, pathogenesis may due central deficiency dopaminergic activity at basal hypothalamus. The observed significant number reflect greater hypothalamic dopamine, as manifested by elevations prolactin levels.
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sci-hub.se 参考文章(22)
Rogerio A. Lobo, Uwe Goebelsmann, Adult manifestation of congenital adrenal hyperplasia due to incomplete 21-hydroxylase deficiency mimicking polycystic ovarian disease American Journal of Obstetrics and Gynecology. ,vol. 138, pp. 720- 726 ,(1980) , 10.1016/0002-9378(80)90095-2
Barry M. Sherman, Curtis E. Harris, Janet Schlechte, Teresa M. Duello, Nicholas S. Halmi, John Van Gilder, Frederick K. Chapler, Daryl K. Granner, Pathogenesis of Prolactin-Secreting Pituitary Adenomas Obstetrical & Gynecological Survey. ,vol. 34, pp. 395- 396 ,(1979) , 10.1097/00006254-197905000-00018
JOSEPH W. GOLDZIEHER, TAZEWELL S. DOZIER, KEITH D. SMITH, EMIL STEINBERGER, Improving the diagnostic reliability of rapidly fluctuating plasma hormone levels by optimized multiple-sampling techniques. The Journal of Clinical Endocrinology and Metabolism. ,vol. 43, pp. 824- 830 ,(1976) , 10.1210/JCEM-43-4-824
H. LEBLANC, G. C. L. LACHELIN, S. ABU-FADIL, S. S. C. YEN, Effects of Dopamine Infusion on Pituitary Hormone Secretion in Humans The Journal of Clinical Endocrinology and Metabolism. ,vol. 43, pp. 668- 674 ,(1976) , 10.1210/JCEM-43-3-668
S. J. JUDD, L. A. RIGG, S. S. C. YEN, The effects of ovariectomy and estrogen treatment on the dopamine inhibition of gonadotropin and prolactin release. The Journal of Clinical Endocrinology and Metabolism. ,vol. 49, pp. 182- 184 ,(1979) , 10.1210/JCEM-49-2-182
S. S. C. YEN, REVIEW ARTICLE: THE POLYCYSTIC OVARY SYNDROME Clinical Endocrinology. ,vol. 12, pp. 177- 208 ,(1980) , 10.1111/J.1365-2265.1980.TB02132.X
E. Knobil, T. Plant, L. Wildt, P. Belchetz, G. Marshall, Control of the rhesus monkey menstrual cycle: permissive role of hypothalamic gonadotropin-releasing hormone Science. ,vol. 207, pp. 1371- 1373 ,(1980) , 10.1126/SCIENCE.6766566
L WILDT, A. HÄUSLER, G. MARSHALL, J. S. HUTCHISON, T. M. PLANT, P. E. BELCHETZ, E. KNOBIL, Frequency and Amplitude of Gonadotropin-Releasing Hormone Stimulation and Gonadotropin Secretion in the Rhesus Monkey Endocrinology. ,vol. 109, pp. 376- 385 ,(1981) , 10.1210/ENDO-109-2-376
M. E. QUIGLEY, J. S. RAKOFF, S. S. C. YEN, Increased luteinizing hormone sensitivity to dopamine inhibition in polycystic ovary syndrome. The Journal of Clinical Endocrinology and Metabolism. ,vol. 52, pp. 231- 234 ,(1981) , 10.1210/JCEM-52-2-231
BarryM. Sherman, Janet Schlechte, NicholasS. Halmi, FrederickK. Chapler, CurtisE. Harris, TeresaM. Duello, John Vangilder, DarylK. Granner, PATHOGENESIS OF PROLACTIN-SECRETING PITUITARY ADENOMAS The Lancet. ,vol. 312, pp. 1019- 1021 ,(1978) , 10.1016/S0140-6736(78)92339-5