Mean platelet volume predicts patency of the infarct-related artery before mechanical reperfusion and short-term mortality in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention.

摘要: Abstract Background and aims Patency of infarct-related artery (IRA) before mechanical reperfusion with primary percutaneous coronary intervention (PPCI) has been associated better prognosis in patients ST-Elevation myocardial infarction (STEMI). Mean platelet volume (MPV) increases STEMI may be increased thrombotic potential. In scheduled for PPCI we sought to assess whether mean (MPV), as measured at admission, correlates “spontaneous” the IRA short-term clinical outcome. Methods Blood samples were obtained on hospital admission 617 consecutive (82% men; age 64 ± 12 years) STEMI, PPCI. 372 (61%) treated GP IIb/IIIa blocker abciximab. The main study endpoint was mortality 30 days. Results MPV significantly lower basal TIMI flow grade 2 -3 compared 0-1 (median, 9 vs. 8.5 fL, p  Conclusion An is an independent predictor both a patent (TIMI or 3 PPCI) 30-day mortality. This marker able identify requiring more aggressive antiplatelet therapy.