Effects of Omega-3 Fatty Acid Supplementation on Neurocognitive Functioning and Mood in Deployed U.S. Soldiers: A Pilot Study

作者: Michael N. Dretsch , Daniel Johnston , Ryan S. Bradley , Holden MacRae , Patricia A. Deuster

DOI: 10.7205/MILMED-D-13-00395

关键词: NeuropsychologyRandomized controlled trialPsychiatryCorn oilNeurocognitiveYoung adultMedicineMoodInternal medicinePlaceboOmega 3 fatty acid supplementationPublic Health, Environmental and Occupational HealthGeneral Medicine

摘要: ABSTRACT Omega-3 fatty acids (FAs) may have neuroprotective properties for psychological health and cognition. The objective of this study was to evaluate the effectiveness omega-3 FAs (eicosapentaenoic + docosahexaenoic; Harris–Schacky [HS]-Omega-3 Index) on neuropsychological functioning among U.S. Soldiers deployed Iraq. This randomized, double-blind, placebo-controlled trial included between ages 18 55 years who were randomly assigned either active treatment group (n = 44) or placebo 34). Active 2.5 g per day eicosapentaenoic docosahexaenoic (Lovaza; GlaxoSmithKline, Research Triangle Park, North Carolina). corn oil ethyl esters. HS-Omega-3 Index, a neurocognitive battery (Central Nervous System-Vital Signs, Morrisville, Carolina), scales assessed at baseline after 60 days treatment. Although results revealed that significantly increased Index (p 0....

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