Consumer Willingness to Pay for Dengue Vaccine (CYD-TDV, Dengvaxia®) in Brazil; Implications for Future Pricing Considerations.
作者： Isabella P Godói , André S Santos , Edna A Reis , Livia LP Lemos , Cristina MR Brandão
关键词: Dengue virus 、 Environmental health 、 Global health 、 Dengue vaccine 、 Population 、 Dengue fever 、 Willingness to pay 、 Inclusion (education) 、 Public health 、 Medicine
摘要: Introduction and Objective: Dengue virus is a serious global health problem with an estimated 3.97 billion people at risk for infection worldwide. In December 2015, the first vaccine (CYD-TDV) dengue prevention was approved in Brazil, developed by Sanofi Pasteur. However, given that will potentially be paid via public system, information need regarding consumers' willingness to pay country as well discussions related possible inclusion of this into system. This objective research. Methods: We conducted cross-sectional study residents Greater Belo Horizonte, Minas Gerais, about their CYD-TDV vaccine. Results: 507 individuals were interviewed. These mostly female (62.4%) had completed high school (62.17%), working (74.4%), private insurance (64.5%) did not have (67.4%). The maximum median value US$33.61 (120.00BRL) complete schedule US$11.20 (40.00BRL) per dose. At price determined Brazil's regulatory chamber pharmaceutical products market commercialization Dengvaxia® three doses, only 17% population expressed Conclusion: Brazil currently one largest markets established key issue. believe manufacturer should asses possibility lower prices reach larger audience among Brazilian population.
frontiersin.org
core.ac.uk
strath.ac.uk
sci-hub.se 参考文章(32)
Kevin J. Boyle, Introduction to Revealed Preference Methods Springer, Dordrecht. pp. 259- 267 ,(2003) , 10.1007/978-94-007-0826-6_8
Sri Rezeki Hadinegoro, Jose Luis Arredondo-García, Maria Rosario Capeding, Carmen Deseda, Tawee Chotpitayasunondh, Reynaldo Dietze, HI Hj Muhammad Ismail, Humberto Reynales, Kriengsak Limkittikul, Doris Maribel Rivera-Medina, Huu Ngoc Tran, Alain Bouckenooghe, Danaya Chansinghakul, Margarita Cortés, Karen Fanouillere, Remi Forrat, Carina Frago, Sophia Gailhardou, Nicholas Jackson, Fernando Noriega, Eric Plennevaux, T Anh Wartel, Betzana Zambrano, Melanie Saville, None, Efficacy and Long-Term Safety of a Dengue Vaccine in Regions of Endemic Disease The New England Journal of Medicine. ,vol. 373, pp. 1195- 1206 ,(2015) , 10.1056/NEJMOA1506223
Ayalew Tefferi, Hagop Kantarjian, S Vincent Rajkumar, Lawrence H Baker, Jan L Abkowitz, John W Adamson, Ranjana Hira Advani, James Allison, Karen H Antman, Robert C Bast, John M Bennett, Edward J Benz, Nancy Berliner, Joseph Bertino, Ravi Bhatia, Smita Bhatia, Deepa Bhojwani, Charles D Blanke, Clara D Bloomfield, Linda Bosserman, Hal E Broxmeyer, John C Byrd, Fernando Cabanillas, George Peter Canellos, Bruce A Chabner, Asher Chanan-Khan, Bruce Cheson, Bayard Clarkson, Susan L Cohn, Gerardo Colon-Otero, Jorge Cortes, Steven Coutre, Massimo Cristofanilli, Walter J Curran, George Q Daley, Daniel J DeAngelo, H Joachim Deeg, Lawrence H Einhorn, Harry P Erba, Francisco J Esteva, Elihu Estey, Isaiah J Fidler, James Foran, Stephen Forman, Emil Freireich, Charles Fuchs, James N George, Morie A Gertz, Sergio Giralt, Harvey Golomb, Peter Greenberg, Jordan Gutterman, Robert I Handin, Samuel Hellman, Paulo Marcelo Hoff, Ronald Hoffman, Waun Ki Hong, Mary Horowitz, Gabriel N Hortobagyi, Clifford Hudis, Jean Pierre Issa, Bruce Evan Johnson, Philip W Kantoff, Kenneth Kaushansky, David Khayat, Fadlo R Khuri, Thomas J Kipps, Margaret Kripke, Robert A Kyle, Richard A Larson, Theodore S Lawrence, Ross Levine, Michael P Link, Scott M Lippman, Sagar Lonial, Gary H Lyman, Maurie Markman, John Mendelsohn, Neal J Meropol, Yoav Messinger, Therese M Mulvey, Susan O’Brien, Roman Perez-Soler, Raphael Pollock, Josef Prchal, Oliver Press, Jerald Radich, Kanti Rai, Saul A Rosenberg, Jacob M Rowe, Hope Rugo, Carolyn D Runowicz, Brenda M Sandmaier, Alan Saven, Andrew I Schafer, Charles Schiffer, Mikkael A Sekeres, Richard T Silver, Lillian L Siu, David P Steensma, F Marc Stewart, Wendy Stock, Richard Stone, Rainer Storb, Louise C Strong, Martin S Tallman, Michael Thompson, Naoto T Ueno, Richard A Van Etten, Julie M Vose, Peter H Wiernik, Eric P Winer, Anas Younes, Andrew D Zelenetz, Charles A LeMaistre, None, In Support of a Patient-Driven Initiative and Petition to Lower the High Price of Cancer Drugs Mayo Clinic proceedings. Mayo Clinic. ,vol. 90, pp. 996- 1000 ,(2015) , 10.1016/J.MAYOCP.2015.06.001
Lee JungSeok Lee JungSeok, V Mogasale, JK Lim, M Carabali, C Sirivichayakul, Dang Duc Anh Dang Duc Anh, Lee KangSung Lee KangSung, Vu Dinh Thiem Vu Dinh Thiem, K Limkittikul, Le Huu Tho Le Huu Tho, ID Velez, JE Osorio, P Chanthavanich, LJ da Silva, BA Maskery, A Multi-country Study of the Household Willingness-to-Pay for Dengue Vaccines: Household Surveys in Vietnam, Thailand, and Colombia PLOS Neglected Tropical Diseases. ,vol. 9, pp. e0003810- ,(2015) , 10.1371/JOURNAL.PNTD.0003810
Cristian Koepfli, Priscila T. Rodrigues, Tiago Antao, Pamela Orjuela-Sánchez, Peter Van den Eede, Dionicia Gamboa, Nguyen van Hong, Jorge Bendezu, Annette Erhart, Céline Barnadas, Arsène Ratsimbasoa, Didier Menard, Carlo Severini, Michela Menegon, Bakri Y. M. Nour, Nadira Karunaweera, Ivo Mueller, Marcelo U. Ferreira, Ingrid Felger, Plasmodium vivax diversity and population structure across four continents PLOS Neglected Tropical Diseases. ,vol. 9, pp. 1- 23 ,(2015) , 10.1371/JOURNAL.PNTD.0003872
Panji Fortuna Hadisoemarto, Marcia C. Castro, Public Acceptance and Willingness-to-Pay for a Future Dengue Vaccine: A Community-Based Survey in Bandung, Indonesia PLoS Neglected Tropical Diseases. ,vol. 7, pp. e2427- ,(2013) , 10.1371/JOURNAL.PNTD.0002427
Brian Godman, Rickard E Malmström, Eduardo Diogene, Andy Gray, Sisira Jayathissa, Angela Timoney, Francisco Acurcio, Ali Alkan, Anna Brzezinska, Anna Bucsics, Stephen M Campbell, Jadwiga Czeczot, Winnie De Bruyn, Irene Eriksson, Faridah Aryani Md Yusof, Alexander E Finlayson, Jurij Fürst, Kristina Garuoliene, Augusto Guerra Júnior, Jolanta Gulbinovič, Saira Jan, Roberta Joppi, Marija Kalaba, Einar Magnisson, Laura McCullagh, Kaisa Miikkulainen, Gabriela Ofierska-Sujkowska, Hanne Bak Pedersen, Gisbert Selke, Catherine Sermet, Susan Spillane, Azuwana Supian, Ilse Truter, Vera Vlahović-Palčevski, Low Ee Vien, Elif H Vural, Janet Wale, Magdałene Władysiuk, Wenjie Zeng, Lars L Gustafsson, None, Are new models needed to optimize the utilization of new medicines to sustain healthcare systems Expert Review of Clinical Pharmacology. ,vol. 8, pp. 77- 94 ,(2015) , 10.1586/17512433.2015.990380
S. T. Buckland, D. C. Macmillan, E. I. Duff, N. Hanley, Estimating mean willingness to pay from dichotomous choice contingent valuation studies The Statistician. ,vol. 48, pp. 109- 124 ,(1999) , 10.1111/1467-9884.00175
Maria G Guzman, Scott B Halstead, Harvey Artsob, Philippe Buchy, Jeremy Farrar, Duane J Gubler, Elizabeth Hunsperger, Axel Kroeger, Harold S Margolis, Eric Martínez, Michael B Nathan, Jose Luis Pelegrino, Cameron Simmons, Sutee Yoksan, Rosanna W Peeling, None, Dengue: a continuing global threat Nature Reviews Microbiology. ,vol. 8, pp. S7- S16 ,(2010) , 10.1038/NRMICRO2460
Daniel Engelman, Karen Kiang, Olivier Chosidow, James McCarthy, Claire Fuller, Patrick Lammie, Roderick Hay, Andrew Steer, , Toward the Global Control of Human Scabies: Introducing the International Alliance for the Control of Scabies PLoS Neglected Tropical Diseases. ,vol. 7, pp. e2167- 4 ,(2013) , 10.1371/JOURNAL.PNTD.0002167