Determinants of 25-Hydroxyvitamin D Concentrations in Infants and Toddlers.

摘要: Background: Resurgence of rickets and recognition excessive prevalence hypovitaminosis D among all age groups in the western hemisphere have refocused attention on vitamin nutrition. Objective: To examine [25-hydroxyvitamin [25(OH)D] < 30ng/mL] characterize the determinants 25(OH)D concentrations 8- to 24-month-old healthy infants toddlers living Pittsburgh, Pennsylvania. Methods: Serum were measured dietary intake D, mode feeding, summertime sun exposure characteristics, skin color (sun-reactive type melanin index) assessed. Results: A total 111 8 children (mean age [±SD] 14.4 [±3.5] months; male, 51%; black, 67%) were studied. concentration was <30 ng/mL 16% (n=18) children. Median (interquartile) 25(OH)D lower who ≥13 months vs. <13 [35 (31, 40.5) 40 (35.8, 44.3) ng/mL, p=0.013]; with sun-reactive IV V I, II, III [36 41) 44 (36.5, 48.5) ng/mL, p=0.001]; examined during fall/winter spring/summer [35.5 (32.5, 38.5) 39 44) p=0.05]. Age and significant independent predictors 25(OH)D. Conclusions: Concentrations tend be fall/winter, who are older (≥13 age) darker tone. Benefits enhancement concentrations during higher need further exploration.