Testing by the “paired-label” antibody binding technique for feline leukemia virus-induced cell surface antigens (FeLV-CSA) on the surface of human rhabdomyosarcoma cells releasing RD-114 virus

作者: Charles W. Boone , Eve C. Church , Robert M. McAllister

DOI: 10.1016/S0042-6822(73)81017-7

关键词: VirologyMolecular biologyVirusBiologyRhabdomyosarcomaAntigen bindingEndogenyCellViral transformationAntigenFeline leukemia virus

摘要: Studies using the sensitive and quantitative paired-label antibody binding technique gave no evidence that human rhabdomyosarcoma cells (RD cells) productively infected with RD-114 virus possessed feline leukemia virus-induced cell surface antigen (FeLV-CSA). The readily detected FeLV-CSA on RD intentionally virus. In addition, rabbit against which bound to of did not bind FeLV-CSA-positive cells. Electron microscopy confirmed a type-C was present in studied. These findings support other biological studies indicating is an endogenous distinct from previously described viruses.

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