作者: Ya-Ming Hou , Xiaolu Yang
关键词: Cytochrome c 、 Cell biology 、 Gene 、 Biology 、 Biochemistry 、 RNA 、 Gene expression 、 Mitochondrion 、 Messenger RNA 、 Apoptosis 、 Transfer RNA
摘要: Abstract Significance: Both transfer RNA (tRNA) and cytochrome c are essential molecules for the survival of cells. tRNA decodes mRNA codons into amino-acid-building blocks in protein all organisms, whereas functions electron transport chain that powers ATP synthesis mitochondrion-containing eukaryotes. Additionally, vertebrates, is released from mitochondria a potent inducer apoptosis, activating apoptotic proteins (caspases) cytoplasm to dismantle A better understanding both an insight regulation cell life death. Recent Advances: recent study showed mitochondrion-released can be removed cell-death pathway by molecules. The direct binding provides mechanism regulate death, beyond its role gene expression. Critical Issues: nature tRNA–cytochrome interaction remains unknown. q...