Cervical screening in the 21st century: the case for human papillomavirus testing of self-collected specimens.

摘要: Cervical screening by Pap smear involves a high rate of false negatives, necessitating frequent testing. Because women do not like the sampling procedure, many avoid being screened. Testing for causative high-risk human papillomavirus (HPV) types, PCR or other technologies, on self-collected (tampon) samples permits to be monitored non-invasively. The negative predictive value HPV testing means greater interval between tests, and thus reduces costs. lends itself primary screening. A kit self-collection return laboratory, followed practitioner notification follow-up if required, should result in wider participation. higher accuracy lead improved cervical cancer prevention.