Narrow-band imaging endoscopy with magnification is useful for detecting metachronous superficial pharyngeal cancer in patients with esophageal squamous cell carcinoma.

摘要: Background and Aims:  Head neck cancers, especially pharyngeal as well esophageal cancers frequently coexist either synchronously or metachronously, but most cases of cancer are detected at an advanced stage resulting in poor prognosis. The aim this study is to evaluate the effectiveness using narrow-band imaging (NBI) endoscopy with magnification for early detection on patients following their treatment squamous cell carcinoma (SCC). Methods:  This case series was conducted National Cancer Center Hospital Tokyo between April October 2005 included 424 consecutive surveillance who had previously undergone chemoradiotherapy (CRT) and/or surgery SCC. Observation region randomly 91 NBI (NBI group) 333 conventional white light (control group). Results:  rate significantly higher (10.9%; 10/91) compared (1.2%; 4/333) (P < 0.0001). In particular, CRT group (12.9%; 7/54) than control (0.5%; 1/191) addition, diagnostic sensitivity, specificity, accuracy, positive predictive value negative were 100% (10/10), 97.5% (79/81), 97.8% (89/91), 83.3% (10/12) (79/79), respectively. Conclusion:  a promising technique detecting superficial treated