Rib infarcts and acute chest syndrome in sickle cell diseases

作者: D.L. Rucknagel , D.L. Rucknagel , K.A. Kalkinyak , M.J. Gelfand

DOI: 10.1016/0140-6736(91)92525-7

关键词: MedicineChest painSurgeryBone InfarctionBone painInfarctionAcute chest syndromeRadiologyPulmonary InfarctionHypoventilationThoraxGeneral Medicine

摘要: In the absence of evidence for pneumonia or pulmonary embolus, primary infarction has been assumed to be cause syndrome chest pain, fever, and infiltrate on X-ray that commonly complicates sickle cell anaemia. To find out whether might due rib infarction, 99mTc-diphosphonate bone scans were done. eleven episodes thus investigated (10 patients) showed segmental areas increased radionuclide uptake in ribs, indicative infarction. A possible sequence events is infarcts are followed by soft tissue reaction, pleuritis, splinting. The resultant hypoventilation leads atelectasis subsequent development radiographic changes acute syndrome. Prevention treatment pain important therapeutic goals.

参考文章(14)
Bernhard Steinberg, Sickle Cell Anemia. Arch. Pathol.. ,vol. 9, ,(1930)
Philip A. Bromberg, Wallace N. Jensen, Arterial oxygen unsaturation in sickle cell disease. The American review of respiratory disease. ,vol. 96, pp. 400- 407 ,(2015) , 10.1164/ARRD.1967.96.3.400
DARLEEN POWARS, JAMES A. WEIDMAN, TAMARA ODOM-MARYON, JOYCE C. NILAND, CAGE JOHNSON, Sickle cell chronic lung disease: prior morbidity and the risk of pulmonary failure. Medicine. ,vol. 67, pp. 66- 76 ,(1988) , 10.1097/00005792-198801000-00005
SAMUEL CHARACHE, Infarction of Bone Marrow in the Sickle Cell Disorders Annals of Internal Medicine. ,vol. 67, pp. 1195- 1200 ,(1967) , 10.7326/0003-4819-67-6-1195
Thomas B. Cole, Intravenous Narcotic Therapy for Children With Severe Sickle Cell Pain Crisis Archives of Pediatrics & Adolescent Medicine. ,vol. 140, pp. 1255- 1259 ,(1986) , 10.1001/ARCHPEDI.1986.02140260057025
Mortimer Poncz, Ellen Kane, Frances M. Gill, Acute chest syndrome in sickle cell disease: etiology and clinical correlates. The Journal of Pediatrics. ,vol. 107, pp. 861- 866 ,(1985) , 10.1016/S0022-3476(85)80176-1
Samuel Charache, 'Acute Chest Syndrome' in Adults With Sickle Cell Anemia Archives of Internal Medicine. ,vol. 139, pp. 67- 69 ,(1979) , 10.1001/ARCHINTE.1979.03630380047016
Elizabeth Barrett-Connor, Pneumonia and Pulmonary Infarction in Sickle Cell Anemia JAMA: The Journal of the American Medical Association. ,vol. 224, pp. 997- 1000 ,(1973) , 10.1001/JAMA.1973.03220210021004
A SAIN, R SHAM, L SILVER, Bone scan in sickle cell crisis. Clinical Nuclear Medicine. ,vol. 3, pp. 85- 90 ,(1978) , 10.1097/00003072-197803000-00003