Phylogenetic analysis reveals dynamic evolution of the poly(A)-binding protein gene family in plants

摘要: The poly(A)-binding protein (PABP) binds the poly(A) tail of eukaryotic mRNAs and functions to maintain integrity mRNA while promoting synthesis through its interaction with translation initiation factor (eIF) 4G eIF4B. PABP is encoded by a single gene in yeast marine algae but during plant evolution family expanded substantially, underwent sequence divergence into three subclasses, acquired tissue-specificity member expression. Although such changes suggest functional specialization, size have complicated an understanding which members may be foundational represent more recent expansions meet specific needs speciation. Here, we examine provide insight these aspects that yield clues function individual members. had two appearance fresh water four non-vascular plants. In lycophytes, first yielding class occurs. earliest share greatest similarity those modern whose expression confined reproductive tissues, suggesting supporting reproductive-associated most conserved this family. A sharing vegetative-associated appears gymnosperms. Further elaboration occurred flowering Expansion began prior colonization land. By tissues higher plants appeared. second appeared gymnosperms all classes fully evolved known basal angiosperm. each further expansion subsequent evolution, especially Brassicaceae, undergoing dynamic evolution.