The early detection of remission in acute myelogenous leukaemia by in vitro cultures.

作者: G. Spitzer , K. A. Dicke , K. B. Mccredie , B. Barlogie

DOI: 10.1111/J.1365-2141.1977.TB00601.X

关键词: In vitroAcute myelogenous leukaemiaAplasiaRemission Induction TherapyBiologyMyeloidLeukemiaChemotherapyImmunologyEarly detection

摘要: Twenty-eight cases of acute myeloid leukaemia without normal colony growth in vitro were serially cultured by an agar culture method during remission induction therapy. Colony formation frequently returned before morphological evidence remission. Without early return drug induced aplasia was prolonged and fatal. Analysis the pattern forming cells may be value designing chemotherapy schedule.

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