作者: Thomas R. Einarson , J. Steven Leeder , Gideon Koren
DOI: 10.1177/106002808802201021
关键词: Meta-analysis 、 Confidence interval 、 Stepwise approach 、 Odds ratio 、 Study Type 、 Medicine 、 Protocol (science) 、 Family medicine 、 Odds 、 Epidemiology
摘要: This article presents a stepwise approach for conducting meta-analysis of epidemiological studies based on proposed guidelines. systematic method is recommended practitioners evaluating in the literature to arrive at an overall quantitative estimate impact treatment. Bendectin used as illustrative example. Meta-analysts should establish priori purpose analysis and complete protocol. protocol be adhered to, all steps performed recorded detail. To aid developing such protocol, we present methods researcher can use perform each 22 six major areas. The confirmed previous traditional narrative reviews that not related teratogenic outcomes humans. summary odds ratio was 1.01 (χ2 = 0.05, p 0.815) with 95 percent confidence interval 0.66–1.55. When were separated according study type, rat...