A Method for Meta-Analysis of Epidemiological Studies

作者: Thomas R. Einarson , J. Steven Leeder , Gideon Koren

DOI: 10.1177/106002808802201021

关键词: Meta-analysisConfidence intervalStepwise approachOdds ratioStudy TypeMedicineProtocol (science)Family medicineOddsEpidemiology

摘要: This article presents a stepwise approach for conducting meta-analysis of epidemiological studies based on proposed guidelines. systematic method is recommended practitioners evaluating in the literature to arrive at an overall quantitative estimate impact treatment. Bendectin used as illustrative example. Meta-analysts should establish priori purpose analysis and complete protocol. protocol be adhered to, all steps performed recorded detail. To aid developing such protocol, we present methods researcher can use perform each 22 six major areas. The confirmed previous traditional narrative reviews that not related teratogenic outcomes humans. summary odds ratio was 1.01 (χ2 = 0.05, p 0.815) with 95 percent confidence interval 0.66–1.55. When were separated according study type, rat...

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