Meta-analysis of parenteral clindamycin dosing regimens.

作者: John P Rovers , A Lane Ilersich , Thomas R Einarson

DOI: 10.1177/106002809502900904

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摘要: Objective:We used meta-analysis to compare clinical cure and success rates for parenteral clindamycin 600 mg q8h or 900 therapy treat adult intraabdominal female pelvic infections.Data Sources:We located English-language articles describing use in humans using MEDLINE, International Pharmaceutical Abstracts, Embase from personal drug information center files, plus all article references.Study Selection:Eligible studies infection at least I aim of a study provided definition outcome. Accepted were comparative trials adults who not critically ill expected die.Data Synthesis:The DerSimonian Laird method was calculate weighted overall (cure improved) along with 95% confidence intervals each dosage infections. Regimens compared respect both su...

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