Beneficial Effects of Endotoxins

摘要: The study of endotoxins has undergone cycles enthusiastic research followed by neglect and revival again due to newly described biological effects attributed endotoxins. It is almost a generally applicable rule that both extremes in such fluctuations the popularity certain re search fields are unjustified. obvious exaggerated expectations will lead disappointments, complete once-exciting field be renewed attention, if scientific basis earlier interest was solid remained so throughout. healing ef fect fever praised as nature's blessed cure, until it discov ered caused bacteria. When became evident careful application one can arrive at therapeutic doses without intro ducing shock hypotension, era therapy began. During this time, indiscriminate use pyrogens widespread high had disillusionment. Since then, terest experienced few more oscillations, with varying wavelengths amplitudes, latest being triggered mitotic effect endotoxin. This led justified excitement among researchers who activation cells lymphatic system consequences thereof, including release important mediator mol ecules. Fever passe, but often ap plication remains well-documented fact."