Chromane derivatives as trpv3 modulators
作者： Javed Yusuf Khatik , Vidya Ganapati Kattige , V. S. Prasada Rao Lingam , Abraham Thomas , Neelima Khairatkar-Joshi
DOI:
关键词: Chromane 、 Transient receptor potential channel 、 TRPV3 、 TRPV 、 Chemistry 、 Pharmacology
摘要: The present invention provides chromane derivatives as transient receptor potential vanilloid (TRPV) modulators. In particular, the compounds described herein are useful for treating or preventing diseases, conditions and/or disorders modulated by TRPV3. Also provided processes preparing herein, intermediates used in their synthesis, pharmaceutical compositions thereof, and methods
lens.org 参考文章(23)
Friedrich Baier, Marcus Hämmerle, Wolfgang Fecke, Ulrich Rester, Axel Dietrich, Olaf Nimz, Beta-secretase inhibitors ,(2003)
Donald C. Liu, Douglas L. Thompson, Gregory A. Carlson, John S. Foster, Mems device using nimn alloy and method of manufacture ,(2006)
Osamu Yaoka, Tsutomu Yamanaka, Toshio Seki, Tohru Nakajima, Benzopyran compound and its pharmaceutical use ,(1989)
Neelima Khairatkar Joshi, Laxmikant Atmaram Gharat, Suresh Mahadev Kadam, Uday Mukund Joshi, Substituted benzofused derivatives and their use as vanilloid receptor ligands ,(2006)
Holger Monenschein, Michael Bartberger, Charles Kreiman, Brian K Albrecht, Matthew Kaller, Michael Croghan, Ted Judd, Craig E. Masse, Thomas Nixey, Stuart C. Chaffee, Lewis Pennington, Vinod F. Patel, Randall Hungate, Daniel La, Thomas Nguyen, Bryant Yang, Matthew Weiss, Patricia Lopez, Stephen Hitchcock, Qiufen Xue, James Brown, Ryan Brown, Scott Harried, Yuan Cheng, Denise Lyn Andersen, Wenge Zhong, Russell Graceffa, Beta-secretase modulators and methods of use ,(2006)
Jiangao Song, Donald R. James, Qiang Cong, Jian Chen, Xianfeng Li, Wei Zhang, Daniel T. W. Chu, Bing Wang, Spiro derivatives as lipoxygenase inhibitors ,(2005)
Anne-Sophie Bessis, Jean-Philippe Rocher, Beatrice Bonnet, Mark Epping-Jordan, Emmanuel Le Poul, Allosteric modulators of metabotropic glutamate receptors ,(2004)
Paul J. Digregorio, Kenneth A. Stauderman, Gonul Velicelebi, Jack Roos, Kari Lynn Ohlsen, Methods of modulating and identifying agents that modulate intracellular calcium ,(2004)
Aldo Andreani, Alberto Leoni, Alessandra Locatelli, Rita Morigi, Mirella Rambaldi, Maurizio Recanatini, Vida Garaliene, Potential antitumor agents. part 291: synthesis and potential coanthracyclinic activity of Imidazo[2,1-b]thiazole guanylhydrazones Bioorganic & Medicinal Chemistry. ,vol. 8, pp. 2359- 2366 ,(2000) , 10.1016/S0968-0896(00)00165-6
Hong‐Zhen Hu, Rui Xiao, Chunbo Wang, Na Gao, Craig K Colton, Jackie D Wood, Michael X Zhu, None, Potentiation of TRPV3 channel function by unsaturated fatty acids. Journal of Cellular Physiology. ,vol. 208, pp. 201- 212 ,(2006) , 10.1002/JCP.20648