The role of sex in cardiac function and disease.

摘要: In the past decade, increasing attention has been paid to importance of sex in etiology cardiac dysfunction. While focus primarily on how modulates atherogenesis, it is becoming clear that both a predictor outcome and an independent risk factor for number other diseases. Animal models human studies have begun shed light mechanisms by which influences function cardiomyocytes health disease. This review will survey current literature diseases are influenced discuss intracellular steroid hormones affect heart function. A theory may regulate myocardial energy metabolism disease susceptibility progression be presented, as well discussion influence outcomes experiments isolated epigenetic marking.