Associations among bronchioloalveolar carcinoma components, positron emission tomographic and computed tomographic findings, and malignant behavior in small lung adenocarcinomas.

作者: Morihito Okada , Shunsuke Tauchi , Koichiro Iwanaga , Takeshi Mimura , Yoshitaka Kitamura

DOI: 10.1016/J.JTCVS.2007.02.023

关键词: MedicineRadiologyPositron emission tomographyCarcinomaHounsfield scaleTomographyNuclear medicineStandardized uptake valueHigh-resolution computed tomographyAdenocarcinomaGround-glass opacity

摘要: Objective The aggressiveness of small adenocarcinomas has not been fully evaluated using integrated positron emission tomography/computed tomography. We investigated malignant according to tomography, high-resolution computed tomographic findings, and the proportions pathologically defined bronchioloalveolar carcinomas in cT1N0M0 lung adenocarcinoma. Methods Sixty consecutive patients with 3 cm or less diameter underwent fluorodeoxyglucose–positron tomograph/computed followed by complete tumor resection. Correlations between proportion carcinoma maximum standardized uptake value on scan/computed scan, ground-glass opacity, shadow disappearance rate were findings compared clinicopathologic features. Results Lymphatic vascular invasion occurred 18 (30%) 13 (22%) patients, respectively, whereas hilar mediastinal lymph nodes 8 (13%). Maximum generally seemed most valuable predictor lymphatic invasion, nodal metastasis rate, ratios. Although association was significant ratio versus value, opacity ratio, (all P R 2 = 0.245) correlated than ( 0.554) 0.671). Conclusions behavior a lower greater aggressive. more powerful clinical biologic performance, independent pathologic proportion. Preoperative assessment tomographic/computed addition scans, might be useful guide treatment strategies for adenocarcinomas.

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