作者: Ian L. Ross , Graham J. Louw
DOI: 10.1002/CA.22422
关键词: Primordium 、 Gonad 、 Kidney 、 Adrenal cortex 、 Endocrinology 、 Adrenal gland 、 Transcription factor 、 Internal medicine 、 Biology 、 Adrenocorticotrophic hormone 、 Congenital adrenal hypoplasia 、 Pathology
摘要: In this mini review, the embryological and functional development of adrenal glands is presented from a molecular perspective. While acknowledging that highly complex series events, processes are described in simple broad strokes single text for reader who interested field but not an active researcher. The origin mesodermal ridge as early fourth week gestation. Between eighth ninth weeks gestation, encapsulated results presence distinct organ. There have been great strides deciphering very complicated aspects gland which multiple transcription factors identified, directing adrenogonadal primordium into cortex, kidney, or bipotential gonad. Adrenocorticotrophic hormone critical hypothalamic-pituitary axis. Several mutations factors, responsible normal found to induce familial syndrome congenital hypoplasia neoplasia.